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Datasheet $199.00 – $429.00
Description
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Bioinformatics
| Size | 20ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab WITHOUT BSA and Azide at 1.0mg/ml |
|---|---|
| Application | IHC |
| Symbol | ARG1 |
| Isotype | kappa, Mouse / IgG3 |
| Species Reactivity | Human. |
| Source | Mouse Monoclonal Antibody |
| Synonyms | |
| Positive Control | 293T cells. Hepatocellular Carcinoma (HCC). |
| Cellular Localization | Cytoplasmic |
| Mol. Weight of Antigen | 35-38kDa |
| Entrez Gene ID | 383 |
| UniProt | P05089 |
| Clone | ARG1/1126 |
Additional Information
| Storage and Stability | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
|---|---|
| Supplied As | 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Limitations | This antibody is available for research use only and is not approved for use in diagnosis. |
| Warranty | There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product. |
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