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Datasheet $199.00 – $429.00
Description
AKR1B1, also designated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Bioinformatics
| Size | 20ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. |
|---|---|
| Application | IF, IHC, Western Blot |
| Symbol | AKR1B1 |
| Isotype | kappa, Mouse / IgG1 |
| Species Reactivity | Human. |
| Source | Mouse Monoclonal Antibody |
| Synonyms | ADR, ALDR1, ALR2, AR |
| Positive Control | 293T, HEK293; A431, HeLa, HepG2, MOLT4, Jurkat and Raji whole cell lysates; Human Kidney; Human colon carcinoma tissue. |
| Cellular Localization | Cytoplasmic |
| Mol. Weight of Antigen | 37kDa |
| Entrez Gene ID | 231 |
| UniProt | P15121 |
| Clone | CPTC-AKR1B1-3 |
Additional Information
| Storage and Stability | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
|---|---|
| Supplied As | 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Limitations | This antibody is available for research use only and is not approved for use in diagnosis. |
| Warranty | There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product. |
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