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Datasheet $199.00 – $429.00
Description
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Bioinformatics
| Size | 20ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab with BSA and Azide at 200ug/ml, 100ug Purified Ab WITHOUT BSA and Azide at 1.0mg/ml |
|---|---|
| Application | IHC |
| Symbol | AIF1 |
| Isotype | kappa, Mouse / IgG1 |
| Species Reactivity | Human. |
| Source | Recombinant Mouse Monoclonal Antibody |
| Synonyms | AIF-1, IBA1, IRT-1, IRT1 |
| Positive Control | Lymph Node, Tonsil or Kidney. |
| Cellular Localization | Cytoplasmic and Cell Surface |
| Mol. Weight of Antigen | 17kDa |
| Entrez Gene ID | 199 |
| UniProt | P55008 |
| Clone | rAIF1/1909 |
Additional Information
| Storage and Stability | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
|---|---|
| Supplied As | 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Limitations | This antibody is available for research use only and is not approved for use in diagnosis. |
| Warranty | There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product. |
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